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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619755
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rac1
Name: Rac family small GTPase 1
Acc ID: CHEBI:27958
Term: cocaine
Definition: A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Chemical ID: MESH:D003042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rac1affects expressionEXP 6480464CTDCocaine affects the expression of RAC1 mRNAPMID:20187946
Rac1increases expressionISORac1 (Mus musculus)6480464CTDCocaine results in increased expression of RAC1 proteinPMID:18952886
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