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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619571
Species: Mus musculus
RGD Object: Gene
Symbol: Mapk3
Name: mitogen-activated protein kinase 3
Acc ID: CHEBI:34445
Term: 4-tert-Octylphenol
Definition: An alkylbenzene that has formula C14H22O.
Chemical ID: MESH:C105260
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk3decreases phosphorylationISOMAPK3 (Homo sapiens)6480464CTD4-tert-octylphenol results in decreased phosphorylation of MAPK3 proteinPMID:26133781
Mapk3multiple interactionsISOMAPK3 (Homo sapiens)6480464CTD[Diethylhexyl Phthalate co-treated with 4-tert-octylphenol] results in decreased phosphorylation of MAPK3 protein; fulvestrant inhibits the reaction [4-tert-octylphenol results in decreased phosphorylation of MAPK3 protein]PMID:26133781
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