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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61867
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp9
Name: caspase 9
Acc ID: CHEBI:135697
Term: sarpogrelate
Definition: null
Chemical ID: MESH:C064294
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp9multiple interactionsISOCasp9 (Mus musculus)6480464CTD[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased cleavage of CASP9 protein]]; sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased cleavage of CASP9 protein]; sarpogrelate inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased cleavage of CASP9 protein]]PMID:34560070 PMID:35202708
Casp9multiple interactionsISOCASP9 (Homo sapiens)6480464CTD[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein]; Clorgyline promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased cleavage of CASP9 protein]]; sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased cleavage of CASP9 protein]; sarpogrelate inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein]; sarpogrelate promotes the reaction [Clorgyline inhibits the reaction [Carbon Tetrachloride results in increased cleavage of CASP9 protein]]PMID:34560070 PMID:35202708
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