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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61865
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lbp
Name: lipopolysaccharide binding protein
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lbpaffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of LBP mRNAPMID:34747641
Lbpincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of LBP mRNAPMID:19692669 PMID:20959002
Lbpaffects expressionISOLbp (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of LBP mRNAPMID:21570461 PMID:26377647
Lbpdecreases expressionISOLbp (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of LBP mRNAPMID:18796159 PMID:28922406 PMID:33956508
Lbpincreases expressionISOLbp (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of LBP mRNAPMID:15591033
Lbpmultiple interactionsISOLbp (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin binds to AHR protein] which results in decreased expression of LBP mRNAPMID:16214954
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