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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61817
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Col1a1
Name: collagen type I alpha 1 chain
Acc ID: CHEBI:6950
Term: mirtazapine
Definition: A tetracyclic antidepressant that has formula C17H19N3.
Chemical ID: MESH:C035133
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Col1a1increases expressionEXP 6480464CTDMirtazapine results in increased expression of COL1A1 mRNAPMID:35066094
Col1a1multiple interactionsEXP 6480464CTD3-methyladenine inhibits the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]]; 3-methyladenine inhibits the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]; Ethanol promotes the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]PMID:35066094
Col1a1increases expressionISOCol1a1 (Mus musculus)6480464CTDMirtazapine results in increased expression of COL1A1 mRNAPMID:35066094
Col1a1multiple interactionsISOCol1a1 (Mus musculus)6480464CTDEthanol promotes the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]PMID:35066094
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