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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61817
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Col1a1
Name: collagen type I alpha 1 chain
Acc ID: CHEBI:34317
Term: 3,3',4,4',5-pentachlorobiphenyl
Definition: A pentachlorobiphenyl in which the chlorines are located at the 3, 4, 5, 3', and 4' positions.
Chemical ID: MESH:C023035
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Col1a1increases expressionEXP 6480464CTD3,4,5,3',4'-pentachlorobiphenyl results in increased expression of COL1A1 mRNAPMID:20959002
Col1a1affects expressionISOCol1a1 (Mus musculus)6480464CTD3,4,5,3',4'-pentachlorobiphenyl affects the expression of COL1A1 mRNAPMID:23994337
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