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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3946
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Urod
Name: uroporphyrinogen decarboxylase
Acc ID: CHEBI:81925
Term: fomesafen
Definition: An N-sulfonylcarboxamide that is N-(methylsulfonyl)benzamide in which the phenyl ring is substituted by a nitro group at position 2 and a 2-chloro-4-(trifluoromethyl)phenoxy group at position 5. A protoporphyrinogen oxidase inhibitor, it was specially developed for use (generally as the corresponding sodium salt, fomesafen-sodium) for post-emergence control of broad-leaf weeds in soya.
Chemical ID: MESH:C088563
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Uroddecreases activityISOUrod (Mus musculus)6480464CTDfomesafen results in decreased activity of UROD proteinPMID:12758057
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