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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3898
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tpm1
Name: tropomyosin 1
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tpm1affects expressionISOTpm1 (Mus musculus)6480464CTDPhenobarbital affects the expression of TPM1 mRNAPMID:23091169
Tpm1decreases expressionISOTpm1 (Mus musculus)6480464CTDPhenobarbital results in decreased expression of TPM1 mRNAPMID:25270620
Tpm1multiple interactionsISOTpm1 (Mus musculus)6480464CTD[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of TPM1 mRNAPMID:24535843
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