GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tp53 | multiple interactions | EXP | | 6480464 | CTD | wortmannin inhibits the reaction [Diethylnitrosamine results in increased expression of TP53 protein]; wortmannin inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of TP53 protein] | PMID:11751435 | Tp53 | decreases phosphorylation | ISO | TP53 (Homo sapiens) | 6480464 | CTD | wortmannin results in decreased phosphorylation of TP53 protein | PMID:22119920 | Tp53 | multiple interactions | ISO | TP53 (Homo sapiens) | 6480464 | CTD | Wortmannin inhibits the reaction [2-chloroethyl ethyl sulfide results in increased phosphorylation of TP53 protein]; Wortmannin inhibits the reaction [3,3'-diindolylmethane results in increased phosphorylation of TP53 protein]; Wortmannin inhibits the reaction [Asbestos, Serpentine results in increased expression of TP53 protein]; Wortmannin inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of TP53 protein]; Wortmannin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of TP53 protein]; Wortmannin inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of TP53 protein]]; Wortmannin inhibits the reaction [Mustard Gas results in increased expression of TP53 protein]; Wortmannin inhibits the reaction [Mustard Gas results in increased phosphorylation of TP53 protein]; Wortmannin inhibits the reaction [Nitric Oxide results in increased phosphorylation of TP53 protein]; Wortmannin inhibits the reaction [Resveratrol results in increased phosphorylation of TP53 protein]; Wortmannin inhibits the reaction [spermine nitric oxide complex results in increased phosphorylation of TP53 protein]; Wortmannin promotes the reaction [arsenic disulfide results in increased expression of and results in increased phosphorylation of TP53 protein]; Wortmannin results in decreased phosphorylation of and results in decreased expression of TP53 protein | PMID:12676607 PMID:15489221 PMID:15837074 PMID:16024610 PMID:17534123 PMID:18298901 PMID:19111594 PMID:22119920 PMID:22290291 | | ||||||||||||||||||||||
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