Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	3889
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Tp53
Name:	tumor protein p53

Acc ID:	CHEBI:27999
Term:	tolbutamide
Definition:	An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Chemical ID:	MESH:D014044

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Tp53	increases expression	EXP		6480464	CTD	Tolbutamide results in increased expression of TP53 mRNA	PMID:16426753

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.