GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | multiple interactions | EXP | | 6480464 | CTD | polydatin inhibits the reaction [Arsenic Trioxide results in increased expression of TNF mRNA] | PMID:29130132 | Tnf | decreases expression | ISO | TNF (Homo sapiens) | 6480464 | CTD | polydatin results in decreased expression of TNF mRNA | PMID:21756928 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; polydatin promotes the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein] | PMID:21756928 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |