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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3876
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: CHEBI:80843
Term: Leonurine
Definition: A trihydroxybenzoic acid that has formula C14H21N3O5.
Chemical ID: MESH:C013587
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfmultiple interactionsEXP 6480464CTDleonurine inhibits the reaction [Iron results in increased expression of TNF protein]PMID:35247364
Tnfmultiple interactionsISOTnf (Mus musculus)6480464CTDleonurine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]PMID:31005592
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