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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3813
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pvr
Name: PVR cell adhesion molecule
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pvrincreases expressionEXP 6480464CTDAcetaminophen results in increased expression of PVR mRNAPMID:33387578
Pvrdecreases expressionISOPVR (Homo sapiens)6480464CTDAcetaminophen results in decreased expression of PVR mRNAPMID:26690555
Pvrincreases expressionISOPvr (Mus musculus)6480464CTDAcetaminophen results in increased expression of PVR mRNAPMID:29246445
Pvrmultiple interactionsISOPvr (Mus musculus)6480464CTDMAP3K5 protein affects the reaction [Acetaminophen results in increased expression of PVR mRNA]; PANX1 gene mutant form promotes the reaction [Acetaminophen results in increased expression of PVR mRNA]PMID:18700144 PMID:29246445
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