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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3752
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Spp1
Name: secreted phosphoprotein 1
Acc ID: CHEBI:34674
Term: dextran sulfate
Definition: A polymer composed of repeating (1->6)-alpha-linked anhydroglucose sulfate units.
Chemical ID: MESH:D016264
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Spp1decreases expressionISOSpp1 (Mus musculus)6480464CTDDextran Sulfate results in decreased expression of SPP1 proteinPMID:35999755
Spp1increases expressionISOSpp1 (Mus musculus)6480464CTDDextran Sulfate results in increased expression of SPP1 mRNAPMID:32033881
Spp1multiple interactionsISOSpp1 (Mus musculus)6480464CTDQingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of SPP1 mRNA]PMID:32033881
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