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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3732
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sod2
Name: superoxide dismutase 2
Acc ID: CHEBI:36241
Term: 3,4-dihydroxybenzoate
Definition: A dihydroxybenzoate having the two hydroxy groups located at the 3- and 4-positions.
Chemical ID: MESH:C520290
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sod2increases expressionISOSod2 (Mus musculus)6480464CTD3,4-dihydroxybenzoate results in increased expression of SOD2 proteinPMID:19679656
Sod2multiple interactionsISOSod2 (Mus musculus)6480464CTD[3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of SOD2 proteinPMID:19679656
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