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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3729
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Snca
Name: synuclein alpha
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sncadecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of SNCA mRNAPMID:25181051 PMID:26186136 PMID:34947998
Sncaincreases expressionEXP 6480464CTDbisphenol A results in increased expression of SNCA mRNAPMID:32145629
Sncadecreases expressionISOSNCA (Homo sapiens)6480464CTDbisphenol A results in decreased expression of SNCA proteinPMID:33376534
Sncadecreases expressionISOSnca (Mus musculus)6480464CTDbisphenol A results in decreased expression of SNCA mRNAPMID:26063408 PMID:32156529
Sncaincreases methylationISOSNCA (Homo sapiens)6480464CTDbisphenol A results in increased methylation of SNCA genePMID:31601247
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