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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3717
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc8a1
Name: solute carrier family 8 member A1
Acc ID: CHEBI:34206
Term: 2,2',5,5'-tetrachlorobiphenyl
Definition: A tetrachlorobiphenyl that is biphenyl in which the hydrogens at the 2 and 5 position of each benzene ring are replaced by chlorines.
Chemical ID: MESH:C009407
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc8a1multiple interactionsISOSlc8a1 (Mus musculus)6480464CTD[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of SLC8A1 mRNAPMID:25510870
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