A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Chemical ID:
MESH:D003042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Cocaine promotes the reaction [SLC6A3 protein affects the uptake of Dopamine]; Cocaine results in increased phosphorylation of and results in increased activity of SLC6A3 protein; vanoxerine affects the reaction [Cocaine affects the expression of SLC6A3 protein]
[Alcohols co-treated with Cocaine] results in increased activity of SLC6A3 protein; Cannabidiol inhibits the reaction [Cocaine results in increased expression of SLC6A3 mRNA]; SLC6A3 mutant form affects the reaction [Cocaine affects the abundance of and affects the uptake of Dopamine]; SLC6A3 protein affects the reaction [[Cocaine co-treated with Alcohols] results in increased uptake of Dopamine]; SLC6A3 protein affects the reaction [Cocaine results in increased uptake of Dopamine]
[Cocaine co-treated with SLC6A3 protein] results in increased expression of FOS protein; [SLC6A3 protein polymorphism affects the susceptibility to Cocaine] which affects the uptake of Dopamine; Butyrates inhibits the reaction [Cocaine inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine]]; Cocaine inhibits the reaction [[Dopamine co-treated with SLC6A3 protein] results in increased expression of FOS mRNA]; Cocaine inhibits the reaction [[Dopamine co-treated with SLC6A3 protein] results in increased expression of FOS protein]; Cocaine inhibits the reaction [Dopamine results in increased activity of SLC6A3 protein]; Cocaine inhibits the reaction [Melitten results in increased localization of SLC6A3 protein]; Cocaine inhibits the reaction [SLC6A3 protein results in increased import of Biogenic Monoamines analog]; Cocaine inhibits the reaction [SLC6A3 protein results in increased import of Fluorescent Dyes]; Cocaine inhibits the reaction [SLC6A3 protein results in increased transport of phenethylamine]; Cocaine inhibits the reaction [SLC6A3 protein results in increased uptake of 4-(4-(dimethylamino)phenyl)-1-methylpyridinium]; Cocaine inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine]; Cocaine promotes the reaction [(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester binds to SLC6A3 protein]
