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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3673
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Shh
Name: sonic hedgehog signaling molecule
Acc ID: CHEBI:67486
Term: quercetin 3-O-beta-D-galactopyranoside
Definition: A quercetin O-glycoside that is quercetin with a beta-D-galactosyl residue attached at position 3. Isolated from Artemisia capillaris, it exhibits hepatoprotective activity.
Chemical ID: MESH:C021304
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Shhincreases expressionEXP 6480464CTDhyperoside results in increased expression of SHH mRNA; hyperoside results in increased expression of SHH proteinPMID:31326407
Shhmultiple interactionsEXP 6480464CTDhyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of SHH mRNA]; hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of SHH protein]PMID:31326407
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