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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3667
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sftpd
Name: surfactant protein D
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sftpddecreases expressionISOSftpd (Mus musculus)6480464CTDLipopolysaccharides results in decreased expression of SFTPD proteinPMID:21724861
Sftpdincreases expressionISOSftpd (Mus musculus)6480464CTDLipopolysaccharides results in increased expression of SFTPD mRNAPMID:21724861
Sftpdmultiple interactionsISOSftpd (Mus musculus)6480464CTD[Ozone co-treated with Lipopolysaccharides] results in increased secretion of SFTPD protein; ERBB4 protein affects the reaction [Lipopolysaccharides results in increased expression of SFTPD mRNA]PMID:21724861 PMID:38749002
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