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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3663
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk10
Name: mitogen activated protein kinase 10
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk10decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of MAPK10 mRNAPMID:25181051
Mapk10increases expressionEXP 6480464CTDbisphenol A results in increased expression of MAPK10 mRNAPMID:30816183 PMID:32528016
Mapk10increases methylationEXP 6480464CTDbisphenol A results in increased methylation of MAPK10 genePMID:28505145
Mapk10multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Genistein] results in increased methylation of MAPK10 genePMID:28505145
Mapk10decreases expressionISOMapk10 (Mus musculus)6480464CTDbisphenol A results in decreased expression of MAPK10 mRNAPMID:30951980 PMID:32156529
Mapk10increases methylationISOMAPK10 (Homo sapiens)6480464CTDbisphenol A results in increased methylation of MAPK10 genePMID:31601247
Mapk10increases phosphorylationISOMAPK10 (Homo sapiens)6480464CTDbisphenol A results in increased phosphorylation of MAPK10 proteinPMID:36232920
Mapk10multiple interactionsISOMAPK10 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] affects the methylation of MAPK10 genePMID:31601247
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