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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3647
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccl3
Name: C-C motif chemokine ligand 3
Acc ID: CHEBI:3374
Term: capsaicin
Definition: A capsaicinoid that has formula C18H27NO3.
Chemical ID: MESH:D002211
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccl3increases expressionEXP 6480464CTDCapsaicin results in increased expression of CCL3 proteinPMID:22150557
Ccl3multiple interactionsEXP 6480464CTD[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CCL3 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CCL3 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CCL3 protein]PMID:22150557
Ccl3multiple interactionsISOCCL3 (Homo sapiens)6480464CTDCapsaicin inhibits the reaction [Palmitic Acid results in increased expression of CCL3 mRNA]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [Capsaicin inhibits the reaction [Palmitic Acid results in increased expression of CCL3 mRNA]]PMID:21745629
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