GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccl2 | increases expression | EXP | | 6480464 | CTD | Carbon Tetrachloride results in increased expression of CCL2 mRNA; Carbon Tetrachloride results in increased expression of CCL2 protein | PMID:22683883 PMID:25478064 PMID:31150632 | Ccl2 | multiple interactions | EXP | | 6480464 | CTD | Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA]; Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 protein]; schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA] | PMID:22683883 PMID:25478064 PMID:31150632 | Ccl2 | increases expression | ISO | Ccl2 (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride results in increased expression of CCL2 mRNA; Carbon Tetrachloride results in increased expression of CCL2 protein | PMID:12500195 PMID:17125873 PMID:18622026 PMID:19913046 PMID:22206755 PMID:24639359 PMID:25432964 PMID:25827057 PMID:27042213 PMID:27339419 PMID:27865854 PMID:29987408 PMID:30056145 PMID:30301768 PMID:30538632 PMID:31919559 PMID:32033504 PMID:36555680 PMID:38042390 | Ccl2 | multiple interactions | ISO | Ccl2 (Mus musculus) | 6480464 | CTD | (4-(((2-(3-fluoro-4-(trifluoromethyl)phenyl)-4-methyl-1,3-thiazol-5-yl)methyl)sulfanyl)-2-methylphenoxy)acetic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA]; ABCB11 inhibits the reaction [NR1H4 gene mutant form promotes the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA]]; Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 protein]; CCL2 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of LTB mRNA]; CCL2 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]; CCL2 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]; CCL2 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]; Dinoprostone inhibits the reaction [PTGS1 gene mutant form promotes the reaction [Carbon Tetrachloride results in increased expression of CCL2 protein]]; DNASE1 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA]; FOXF1 protein affects the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA]; ginsan inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA]; HAS3 protein affects the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA]; HAS3 protein affects the reaction [Carbon Tetrachloride results in increased expression of CCL2 protein]; Ivermectin inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA]; MGLL protein affects the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA]; NR1H4 gene mutant form promotes the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA]; obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA]; PANX1 protein affects the reaction [Carbon Tetrachloride results in increased expression of CCL2 protein]; PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA]; PTGS1 gene mutant form promotes the reaction [Carbon Tetrachloride results in increased expression of CCL2 protein]; SC 560 promotes the reaction [Carbon Tetrachloride results in increased expression of CCL2 protein]; STF 083010 inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA]; TBXA2R protein affects the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA]; TBXA2R protein affects the reaction [Carbon Tetrachloride results in increased expression of CCL2 protein]; tianhuang inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA]; tianhuang inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 protein] | PMID:12500195 PMID:17125873 PMID:18622026 PMID:19913046 PMID:22206755 PMID:25432964 PMID:27042213 PMID:27865854 PMID:28505368 PMID:29987408 PMID:30056145 PMID:30301768 PMID:30538632 PMID:32033504 PMID:36555680 PMID:38042390 | | ||||||||||||||||||||||
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