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GENE - TERM ANNOTATION REPORT

RGD ID: 3531
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Raf1
Name: Raf-1 proto-oncogene, serine/threonine kinase
Acc ID: DOID:12930
Term: dilated cardiomyopathy
Definition: An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Dilated_cardiomyopathy "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Raf1 ISORAF1 (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:24777450
Raf1 ISORAF1 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Primary dilated cardiomyopathyPMID:24777450 PMID:25741868 PMID:28492532
Raf1 ISORAF1 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Primary dilated cardiomyopathyPMID:24777450 PMID:25741868 PMID:28492532 PMID:29493581
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