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GENE - TERM ANNOTATION REPORT

RGD ID: 3531
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Raf1
Name: Raf-1 proto-oncogene, serine/threonine kinase
Acc ID: DOID:0060581
Term: Noonan syndrome 3
Definition: A Noonan syndrome that has_material_basis_in heterozygous mutation in the KRAS gene. (DO)
Definition Source(s): https://www.ncbi.nlm.nih.gov/pubmed/16474405 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Raf1 ISORAF1 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Noonan syndrome 3PMID:17603482 PMID:22821648 PMID:25741868 PMID:28492532 PMID:30157809 PMID:30732632
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