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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3453
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptprf
Name: protein tyrosine phosphatase, receptor type, F
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptprfaffects expressionEXP 6480464CTDbisphenol A affects the expression of PTPRF mRNAPMID:25181051 PMID:30903817 PMID:32145629
Ptprfdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of PTPRF mRNAPMID:35192832
Ptprfincreases methylationEXP 6480464CTDbisphenol A results in increased methylation of PTPRF genePMID:28505145
Ptprfdecreases expressionISOPTPRF (Homo sapiens)6480464CTDbisphenol A results in decreased expression of PTPRF proteinPMID:37664457
Ptprfdecreases methylationISOPtprf (Mus musculus)6480464CTDbisphenol A results in decreased methylation of PTPRF promoterPMID:27312807
Ptprfincreases expressionISOPtprf (Mus musculus)6480464CTDbisphenol A results in increased expression of PTPRF mRNAPMID:32156529
Ptprfmultiple interactionsISOPTPRF (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in decreased methylation of PTPRF genePMID:31601247
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