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GENE - TERM ANNOTATION REPORT

RGD ID: 3423
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Psap
Name: prosaposin
Acc ID: GO:0005764
Term: lysosome
Definition: A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
Definition Source(s): GOC:mah, ISBN:0198506732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Psaplocated_inISOPsap (Mus musculus)1624291RGD PMID:12867159 PMID:19732768 PMID:29514215

PMID:12867159 PMID:19732768 PMID:29514215
Psaplocated_inISOPSAP (Homo sapiens)1624291RGD PMID:22431521 PMID:26370502 PMID:28541286

PMID:22431521 PMID:26370502 PMID:28541286
Psapis_active_inIBAMGI:97783 or PANTHER:PTN000159370 or UniProtKB:P076021600115GO_CentralGO_REF:0000033

GO_REF:0000033
Psaplocated_inIEAUniProtKB-SubCell:SL-01581600115UniProtGO_REF:0000044

GO_REF:0000044
Psaplocated_inISSUniProtKB:P076021600115UniProtGO_REF:0000024

GO_REF:0000024
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