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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3343
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Plau
Name: plasminogen activator, urokinase
Acc ID: CHEBI:52288
Term: 1-octadec-9-enoylglycero-3-phosphate
Definition: A 2-lysophosphatidic acid that has formula C21H41O7P.
Chemical ID: MESH:C032881
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Plauincreases expressionISOPLAU (Homo sapiens)6480464CTDlysophosphatidic acid results in increased expression of PLAU mRNAPMID:23127547
Plaumultiple interactionsISOPLAU (Homo sapiens)6480464CTDgefitinib inhibits the reaction [lysophosphatidic acid results in increased expression of PLAU mRNA]; gefitinib promotes the reaction [resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of PLAU mRNA]]; resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of PLAU mRNA]; resveratrol promotes the reaction [gefitinib inhibits the reaction [lysophosphatidic acid results in increased expression of PLAU mRNA]]PMID:23127547
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