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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3284
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pdgfra
Name: platelet derived growth factor receptor alpha
Acc ID: CHEBI:46680
Term: serpentine asbestos
Definition: null
Chemical ID: MESH:D017632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdgfraincreases expressionEXP 6480464CTDAsbestos, Serpentine results in increased expression of PDGFRA mRNA; Asbestos, Serpentine results in increased expression of PDGFRA proteinPMID:8392089 PMID:9603151
Pdgfradecreases expressionISOPdgfra (Mus musculus)6480464CTDAsbestos, Serpentine results in decreased expression of PDGFRA mRNAPMID:16251409
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