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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3267
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pck1
Name: phosphoenolpyruvate carboxykinase 1
Acc ID: CHEBI:50095
Term: bucladesine
Definition: A 3',5'-cyclic purine nucleotide that is the 2'-butanoate ester and 6-N-butanoyl derivative of 3',5'-cyclic AMP.
Chemical ID: MESH:D003994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pck1increases expressionEXP 6480464CTDBucladesine results in increased expression of PCK1 mRNAPMID:1371108
Pck1multiple interactionsEXP 6480464CTDLithium Chloride inhibits the reaction [Bucladesine results in increased expression of PCK1 mRNA]PMID:1371108
Pck1increases expressionISOPck1 (Mus musculus)6480464CTDBucladesine results in increased expression of PCK1 mRNAPMID:24428821
Pck1multiple interactionsISOPck1 (Mus musculus)6480464CTDMetformin inhibits the reaction [Bucladesine results in increased expression of PCK1 mRNA]PMID:24428821
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