GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Serpine1 | increases expression | EXP | | 6480464 | CTD | Streptozocin results in increased expression of SERPINE1 mRNA; Streptozocin results in increased expression of SERPINE1 protein | PMID:15322501 PMID:16973718 PMID:19369054 | Serpine1 | multiple interactions | EXP | | 6480464 | CTD | benazepril inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]; Trientine inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]; Zinc inhibits the reaction [Streptozocin results in increased expression of SERPINE1 protein] | PMID:15322501 PMID:16973718 PMID:19369054 | Serpine1 | increases expression | ISO | Serpine1 (Mus musculus) | 6480464 | CTD | Streptozocin results in increased expression of SERPINE1; Streptozocin results in increased expression of SERPINE1 mRNA; Streptozocin results in increased expression of SERPINE1 protein | PMID:16731828 PMID:21778425 PMID:22744176 PMID:24967692 | Serpine1 | multiple interactions | ISO | Serpine1 (Mus musculus) | 6480464 | CTD | SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SERPINE1]; Streptozocin promotes the reaction [MAP3K5 protein results in increased expression of SERPINE1 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of SERPINE1 protein] | PMID:16731828 PMID:21778425 PMID:22744176 PMID:24967692 | | ||||||||||||||||||||||
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