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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3185
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nos2
Name: nitric oxide synthase 2
Acc ID: CHEBI:2700
Term: anandamide
Definition: An N-acylethanolamine 20:4 resulting from the formal condensation of carboxy group of arachidonic acid with the amino group of ethanolamine.
Chemical ID: MESH:C078814
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nos2multiple interactionsISONos2 (Mus musculus)6480464CTDanandamide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; anandamide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]PMID:11891798 PMID:15748152
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