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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3046
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk3
Name: mitogen activated protein kinase 3
Acc ID: CHEBI:81221
Term: Kukoamine B
Definition: An amine that has formula C28H42N4O6.
Chemical ID: MESH:C557784
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk3multiple interactionsISOMAPK3 (Homo sapiens)6480464CTDkukoamine B inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]; kukoamine B inhibits the reaction [N-Methylaspartate results in decreased phosphorylation of MAPK3 protein]PMID:26065936 PMID:26164594
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