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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3010
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lipe
Name: lipase E, hormone sensitive type
Acc ID: CHEBI:17747
Term: bis(2-ethylhexyl) phthalate
Definition: A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:D004051
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lipeincreases expressionISOLipe (Mus musculus)6480464CTDDiethylhexyl Phthalate results in increased expression of LIPE mRNAPMID:32522588
Lipemultiple interactionsISOLipe (Mus musculus)6480464CTD[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of LIPE mRNA; [Dietary Fats co-treated with Dietary Sucrose] promotes the reaction [[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of LIPE mRNA]PMID:30722647
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