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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3001
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lepr
Name: leptin receptor
Acc ID: CHEBI:16199
Term: urea
Definition: A carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O).
Chemical ID: MESH:D014508
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Leprincreases abundanceISOLepr (Mus musculus)6480464CTDLEPR gene mutant form results in increased abundance of UreaPMID:29988851 PMID:36066211
Leprmultiple interactionsISOLepr (Mus musculus)6480464CTDGlucagon analog inhibits the reaction [LEPR gene mutant form results in increased abundance of Urea]; swietenine inhibits the reaction [LEPR gene mutant form results in increased abundance of Urea]PMID:29988851 PMID:36066211
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