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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2901
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il6
Name: interleukin 6
Acc ID: CHEBI:149906
Term: Tanshinone I
Definition: null
Chemical ID: MESH:C021751
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il6multiple interactionsISOIl6 (Mus musculus)6480464CTDtanshinone analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]PMID:29906494
Il6multiple interactionsISOIL6 (Homo sapiens)6480464CTDtanshinone analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; tanshinone inhibits the reaction [Particulate Matter results in increased expression of IL6 protein]PMID:29906494 PMID:35304817
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