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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2899
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il4r
Name: interleukin 4 receptor
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il4rincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of IL4R mRNA; Tetrachlorodibenzodioxin results in increased expression of IL4RA mRNAPMID:18796159 PMID:33387578 PMID:34747641
Il4raffects expressionISOIl4ra (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of IL4RA mRNAPMID:21570461 PMID:28922406
Il4rincreases expressionISOIl4ra (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of IL4RA mRNAPMID:19933214
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