GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | multiple interactions | EXP | | 6480464 | CTD | [Thapsigargin co-treated with dapagliflozin] inhibits the reaction [IL1B protein results in increased expression of BAX protein]; Thapsigargin inhibits the reaction [dapagliflozin inhibits the reaction [IL1B protein results in decreased expression of SIRT1 mRNA]]; Thapsigargin inhibits the reaction [dapagliflozin inhibits the reaction [IL1B protein results in increased expression of EIF2AK3 mRNA]]; Thapsigargin inhibits the reaction [dapagliflozin inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]] | PMID:37741535 | Il1b | increases expression | ISO | IL1B (Homo sapiens) | 6480464 | CTD | Thapsigargin results in increased expression of IL1B mRNA | PMID:30796460 | Il1b | multiple interactions | ISO | Il1b (Mus musculus) | 6480464 | CTD | Thapsigargin inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA] | PMID:18799549 | | ||||||||||||||||||||||
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