GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | increases expression | EXP | | 6480464 | CTD | Zearalenone results in increased expression of IL1B protein modified form | PMID:31586597 | Il1b | multiple interactions | EXP | | 6480464 | CTD | 3-methyladenine promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form]; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form]; NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of IL1B protein modified form]; Sirolimus inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form] | PMID:31586597 | Il1b | increases expression | ISO | Il1b (Mus musculus) | 6480464 | CTD | Zearalenone results in increased expression of IL1B; Zearalenone results in increased expression of IL1B mRNA; Zearalenone results in increased expression of IL1B protein | PMID:25682699 PMID:36161741 PMID:38159578 | Il1b | increases secretion | ISO | Il1b (Mus musculus) | 6480464 | CTD | Zearalenone results in increased secretion of IL1B protein | PMID:30270565 | Il1b | multiple interactions | ISO | Il1b (Mus musculus) | 6480464 | CTD | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [corynoline inhibits the reaction [Zearalenone results in increased expression of IL1B protein]]; [Dextran Sulfate co-treated with Zearalenone] results in increased secretion of IL1B protein; corynoline inhibits the reaction [Zearalenone results in increased expression of IL1B protein]; Lipopolysaccharides promotes the reaction [Zearalenone results in increased expression of IL1B mRNA]; Lycopene inhibits the reaction [Zearalenone results in increased expression of IL1B]; Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of IL1B mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased secretion of IL1B protein] | PMID:16687389 PMID:25682699 PMID:30270565 PMID:36161741 PMID:38159578 | Il1b | multiple interactions | ISO | IL1B (Homo sapiens) | 6480464 | CTD | [Zearalenone co-treated with deoxynivalenol] results in increased expression of IL1B mRNA | PMID:35090964 | | ||||||||||||||||||||||
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