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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2872
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Igfbp1
Name: insulin-like growth factor binding protein 1
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Igfbp1affects expressionISOIgfbp1 (Mus musculus)6480464CTDsodium arsenite affects the expression of IGFBP1 mRNAPMID:16507464
Igfbp1decreases expressionISOIgfbp1 (Mus musculus)6480464CTDsodium arsenite results in decreased expression of IGFBP1 mRNAPMID:17350061 PMID:17451858 PMID:33933676
Igfbp1increases expressionISOIgfbp1 (Mus musculus)6480464CTDsodium arsenite results in increased expression of IGFBP1 mRNAPMID:14691202 PMID:15276417 PMID:17077188
Igfbp1multiple interactionsISOIgfbp1 (Mus musculus)6480464CTD[Diethylstilbestrol co-treated with sodium arsenite] results in increased expression of IGFBP1 mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IGFBP1 mRNAPMID:16368122 PMID:19665456
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