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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2857
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Icam1
Name: intercellular adhesion molecule 1
Acc ID: CHEBI:9434
Term: telmisartan
Definition: A member of the class of benzimidazoles used widely in the treatment of hypertension.
Chemical ID: MESH:C084178
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Icam1multiple interactionsEXP 6480464CTDtelmisartan inhibits the reaction [Daunorubicin results in increased expression of ICAM1 protein]PMID:20888384
Icam1multiple interactionsISOIcam1 (Mus musculus)6480464CTDtelmisartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]PMID:17724226
Icam1multiple interactionsISOICAM1 (Homo sapiens)6480464CTDtelmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]PMID:22124178
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