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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2835
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsd11b2
Name: hydroxysteroid 11-beta dehydrogenase 2
Acc ID: CHEBI:8428
Term: procainamide
Definition: A benzamide that is 4-aminobenzamide substituted on the amide N by a 2-(diethylamino)ethyl group. It is a pharmaceutical antiarrhythmic agent used for the medical treatment of cardiac arrhythmias.
Chemical ID: MESH:D011342
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsd11b2increases expressionEXP 6480464CTDProcainamide results in increased expression of HSD11B2 mRNAPMID:15489962
Hsd11b2increases expressionISOHSD11B2 (Homo sapiens)6480464CTDProcainamide results in increased expression of HSD11B2 mRNAPMID:15489962
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