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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2834
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsd11b1
Name: hydroxysteroid 11-beta dehydrogenase 1
Acc ID: CHEBI:80774
Term: tauroursodeoxycholic acid
Definition: A bile acid taurine conjugate derived from ursoodeoxycholic acid.
Chemical ID: MESH:C031655
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsd11b1decreases expressionEXP 6480464CTDursodoxicoltaurine results in decreased expression of HSD11B1 mRNAPMID:15885361
Hsd11b1multiple interactionsEXP 6480464CTDursodoxicoltaurine inhibits the reaction [Nicotine results in increased expression of HSD11B1 mRNA]PMID:26803847
Hsd11b1decreases abundanceISOHsd11b1 (Mus musculus)6480464CTDHSD11B1 gene mutant form results in decreased abundance of ursodoxicoltaurinePMID:25061560
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