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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2834
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsd11b1
Name: hydroxysteroid 11-beta dehydrogenase 1
Acc ID: CHEBI:50838
Term: drospirenone
Definition: A steroid lactone that has formula C24H30O3.
Chemical ID: MESH:C035144
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsd11b1multiple interactionsISOHSD11B1 (Homo sapiens)6480464CTDdrospirenone inhibits the reaction [HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]PMID:28257955
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