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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2810
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hnf4a
Name: hepatocyte nuclear factor 4, alpha
Acc ID: CHEBI:42758
Term: aldehydo-D-glucose
Definition: The open chain form of D-glucose.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hnf4adecreases expressionISOHNF4A (Homo sapiens)6480464CTDGlucose results in decreased expression of HNF4A mRNAPMID:17992261
Hnf4aincreases expressionISOHnf4a (Mus musculus)6480464CTDGlucose results in increased expression of HNF4A mRNAPMID:31525975
Hnf4amultiple interactionsISOHNF4A (Homo sapiens)6480464CTDCerulenin inhibits the reaction [Glucose results in decreased expression of HNF4A mRNA]; Glucose affects the reaction [HNF4A protein binds to SHBG promoter]PMID:17992261
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