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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2806
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hmox1
Name: heme oxygenase 1
Acc ID: CHEBI:35189
Term: sesquiterpene
Definition: A C15 terpene.
Chemical ID: MESH:D012717
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmox1increases expressionISOHmox1 (Mus musculus)6480464CTDSesquiterpenes analog results in increased expression of HMOX1 mRNA; Sesquiterpenes analog results in increased expression of HMOX1 proteinPMID:30672058
Hmox1increases expressionISOHMOX1 (Homo sapiens)6480464CTDSesquiterpenes analog results in increased expression of HMOX1 mRNA; Sesquiterpenes analog results in increased expression of HMOX1 proteinPMID:30672058
Hmox1multiple interactionsISOHMOX1 (Homo sapiens)6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Sesquiterpenes analog results in increased expression of HMOX1 protein]; Lithium Chloride promotes the reaction [Sesquiterpenes analog results in increased expression of HMOX1 protein]; NFE2L2 protein promotes the reaction [Sesquiterpenes analog results in increased expression of HMOX1 protein]PMID:30672058
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