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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2790
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hdc
Name: histidine decarboxylase
Acc ID: CHEBI:7772
Term: omeprazole
Definition: A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
Chemical ID: MESH:D009853
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hdcaffects expressionEXP 6480464CTDOmeprazole affects the expression of HDC mRNAPMID:19483382
Hdcincreases expressionEXP 6480464CTDOmeprazole results in increased expression of HDC mRNAPMID:12763636
Hdcincreases stabilityEXP 6480464CTDOmeprazole results in increased stability of HDC proteinPMID:12763636
Hdcmultiple interactionsEXP 6480464CTDOmeprazole results in increased expression of and results in increased activity of HDC proteinPMID:12763636
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