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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2765
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gstt1
Name: glutathione S-transferase theta 1
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gstt1decreases expressionISOGstt1 (Mus musculus)6480464CTDEstradiol results in decreased expression of GSTT1 mRNAPMID:14664709
Gstt1decreases expressionISOGSTT1 (Homo sapiens)6480464CTDEstradiol results in decreased expression of GSTT1 mRNAPMID:23019147 PMID:31614463
Gstt1multiple interactionsISOGSTT1 (Homo sapiens)6480464CTD[Progesterone co-treated with Estradiol] results in decreased expression of GSTT1 mRNAPMID:17404688
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