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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2753
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gsta1
Name: glutathione S-transferase alpha 1
Acc ID: CHEBI:38940
Term: sunitinib
Definition: A pyrrole that has formula C22H27FN4O2.
Chemical ID: MESH:C473478
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gsta1increases expression ISOGSTA1 (Homo sapiens)150537096RGDSunitinib increases expression of GSTA1 mRNA in breast epithelium 
Gsta1affects expressionEXP 6480464CTDsunitinib affects the expression of GSTA1 mRNAPMID:26797788
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