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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2729
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gpx1
Name: glutathione peroxidase 1
Acc ID: CHEBI:77006
Term: 17beta-estradiol 3-benzoate
Definition: A benzoate ester resulting from the formal condensation of benzoic acid with the phenolic hydroxy group of 17beta-estradiol.
Chemical ID: MESH:C074283
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gpx1decreases expressionEXP 6480464CTDestradiol 3-benzoate results in decreased expression of GPX1 mRNAPMID:24316378
Gpx1multiple interactionsEXP 6480464CTDQuercetin inhibits the reaction [estradiol 3-benzoate results in decreased expression of GPX1 mRNA]PMID:24316378
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